Basic Structure of an Amino Acid

Basic Structure

All amino acids found in proteins have this basic structure, differing only in the structure of the R-group or the side chain.

The simplest, and smallest, amino acid found in proteins is glycine for which the R-group is hydrogen (H).


L-isomer
In proteins, only the L-isomer is found normally.

As you travel onward (from the carbonyl carbon to the amino group), the R group of L-amino acids will be on the left as shown in the molecular graphic on the right


Essential amino acids

Humans can produce 10 of the 20 amino acids. The others must be supplied in the food. Failure to obtain enough of even 1 of the 10 essential amino acids, those that we cannot make, results in degradation of the body's proteins—muscle and so forth—to obtain the one amino acid that is needed. Unlike fat and starch, the human body does not store excess amino acids for later use—the amino acids must be in the food every day.

The 10 amino acids that we can produce are alanine, asparagine, aspartic acid, cysteine, glutamic acid, glutamine, glycine, proline, serine and tyrosine. Tyrosine is produced from phenylalanine, so if the diet is deficient in phenylalanine, tyrosine will be required as well. The essential amino acids are argentine (required for the young, but not for adults), histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine. These amino acids are required in the diet. Plants, of course, must be able to make all the amino acids. Humans, on the other hand, do not have all the enzymes required for the biosynthesis of all of the amino acids.

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